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Better Face Line

Rejuran in Seoul — polynucleotide skin healer for thin, sensitive skin

Restoring Skin’s Self-Recovery Environment

Rejuran — Better Face Line at VOS Dermatology Clinic, Gangnam Seoul

Overview

Rejuran in Seoul is a polynucleotide (PN) skin booster derived from purified salmon DNA, chosen for its high biocompatibility with human tissue. Micro-injected into the dermis, PN restores the environment your skin needs to repair itself — fibroblast activity, barrier strength, hydration — so the skin recovers rather than being filled.

VOS Dermatology offers the full line: Rejuran Healer for face and neck, Rejuran i for the eye area, and Rejuran HB+ with hyaluronic acid and lidocaine for deeper hydration and less discomfort. Three sessions a month apart are the standard protocol, with results typically lasting over six months; individual outcomes vary.

Who it’s for

Is Rejuran right for you?

  • Those with thinner, more sensitive skin
  • Those concerned about fine lines and rough texture
  • Those who want natural skin improvement
  • Those experiencing low skin condition due to loss of elasticity
  • Those seeking to improve fine lines
  • Those seeking to enhance skin elasticity
How it works

What Rejuran does in the skin

01Maximizing Skin Regeneration by Stimulating Fibroblasts

Rejuran is a rejuvenating injection that delivers Polynucleotide (PN), a key ingredient for skin regeneration, directly into the dermis through microinjections. This procedure promotes cell regeneration and repairs damaged skin. Damaged and aging skin suffers from reduced activity, main to weakened basal cells in the epidermis and impaired fibroblasts in the dermis, which are responsible for producing collagen, elastin, and hyaluronic acid. This results in a weakened skin barrier, increased sensitivity, dryness, and issues such as loss of elasticity, enlarged pores, wrinkles, and pigmentation. Rejuran enhances the skin’s natural ability to regenerate without artificial stimulation, elevating the skin’s overall condition from within. 1: Polynucleotide (PN) is injected directly into the dermal layer. 2: Collagen production is stimulated, repairing damaged skin. 3: Three sessions at one-month intervals provide skin regeneration effects lasting over six months.

02Safe, Key Ingredient Derived from Salmon DNA

The primary ingredient of Rejuran, Polynucleotide (PN), is derived from purified DNA extracted from salmon, known for its high biocompatibility with humans. This ensures safety without causing foreign body reactions.

03personalized Product Lines for Various Skin Concerns

Rejuran offers customized product lines to address a wide range of skin concerns: Rejuran Healer Advanced skin regeneration treatment for face and neck, improving skin barrier function and reducing wrinkles. Rejuran i Targeted solution for the eye area, addressing fine lines and dark circles. Rejuran HB+ Enhanced formula with hyaluronic acid for superior hydration and barrier protection. Features lidocaine for 53% less discomfort during treatment. Rejuran treatments restore skin elasticity and radiance, promoting a naturally youthful appearance. Rejuran Healer Rejuran i Rejuran HB+ Key Ingredient Polynucleotide (PN) Polynucleotide (PN) Polynucleotide (PN), Lidocaine Use Overall skin regeneration Eye area treatment Deep hydration and skin barrier enhancement Key Features Targets broad areas like face and neck, improves elasticity, strengthens skin barrier, and reduces fine lines. Formulated for sensitive eye skin, reduces fine lines and dark circles. Combines Rejuran Healer’s effects with intense hydration, pain relief, and enhanced clinical wrinkle improvement.

04Outstanding Clinical Results for Wrinkle Improvement

Rejuran treatment has shown significant improvements in wrinkles and skin elasticity, restoring a healthy, radiant glow for a youthful appearance. Experience natural skin enhancement with Rejuran. 10 Weeks: 25% wrinkle improvement 16 Weeks: 32% wrinkle improvement 28 Weeks: 36% wrinkle improvement

What to expect

Session, comfort, downtime, results

Session time
About 30 minutes
Comfort
Numbing cream; HB+ contains lidocaine (53% less discomfort per manufacturer data cited on vos.co.kr)
Downtime
Minor swelling, bruising or redness for 2–3 days is possible
Results
Improvement within 12 weeks; lasts about 6 months; 3 sessions recommended (varies)
  • Improves Skin Tone, Texture, Elasticity, and Hydration
  • Achieves results lasting over 6 months with 3 sessions at monthly intervals
  • Treatment Time: within 30 minutes
  • Simple topical anesthesia
  • Immediate return to daily activities post-treatment (minor swelling, bruising, or redness may occur for 2–3 days)

Results, timing and recovery vary from person to person. Nothing here replaces an in-person consultation.

Pricing

Rejuran Pricing at VOS

Based on VOS Dermatology’s official price list as of October 16, 2026.

Prices are in KRW and are subject to 10% VAT. The same pricing applies to all patients, regardless of nationality.

The appropriate dosage and number of treatment sessions will be determined during your consultation with Dr. Kim.

Rejuran Healer

Polynucleotide (PN)
  • 2 mL₩400,000
  • From 8 mL₩300,000per 2 mL

Rejuran HB

Polynucleotide (PN) + Hyaluronic Acid (HA) + Lidocaine
  • 1 mL₩350,000
  • From 4 mL₩300,000per 1 mL

Rejuran Eye

Polynucleotide (PN)
  • 1 mL₩400,000
  • From 3 mL₩300,000per 1 mL

REJURAN Face Package (6 treatments)

  • REJURAN Healer (Face) 6 cc — ₩1,320,000
  • REJURAN Eye (eye wrinkles) 2 cc — ₩880,000
  • REJURAN HB (lips) 1 cc — ₩385,000
  • Package₩2,585,000₩2,068,00020% off

REJURAN Face + Neck Package (12 treatments)

  • REJURAN Healer (Face) 6 cc — ₩1,320,000
  • REJURAN Eye (eye wrinkles) 2 cc — ₩880,000
  • REJURAN HB (lips) 1 cc — ₩385,000
  • REJURAN Healer (Neck) 6 cc — ₩1,320,000
  • REJURAN Healer (Décolleté) 6 cc — ₩1,320,000
  • Package₩5,225,000₩3,657,50030% off
Packages that include Rejuran are listed on the full price list.Full price list
Often combined or compared

Related treatments

  • Juvelook — Better Face Line at VOS Dermatology Clinic, Gangnam Seoul

    Juvelook

    Designing the skin’s natural regenerative power

    Fine wrinkle improvementSkin texture improvement
    • Those who have started to develop fine wrinkles around the eyes, forehead, mouth, etc.
    • For those with rough skin surfaces and uneven texture

    From ₩1,000,000 before VAT

    How Juvelook works
  • Retizen — Better Face Line at VOS Dermatology Clinic, Gangnam Seoul

    Retizen

    A true collagen skinbooster that firms from within the skin

    Skin Elasticity ImprovementWrinkle Improvement
    • Those concerned about dry, dull skin
    • Those concerned about sagging pores and fine lines
    How Retizen works
  • Hilo Wave — Better Skin Glow at VOS Dermatology Clinic, Gangnam Seoul

    Hilo Wave

    Skin quality improvement considering both skin moisture and structure

    Volume ImprovementSkin Elasticity Improvement
    • Those who want overall skin quality improvement
    • Those worried about needling, marks, swelling, or embossing

    From ₩600,000 before VAT

    How Hilo Wave works
FAQ

Questions patients ask about Rejuran

How much does Rejuran cost in Seoul?
On VOS Dermatology's official price list (October 16, 2026) — Rejuran Healer: 2 mL ₩400,000, From 8 mL ₩300,000. Prices are in KRW before 10% VAT and are the same for all nationalities. The number of shots, vials or sessions that suits you is decided with Dr. Kim at consultation, and packages may lower the per-unit price. See the full price list at /pricing.
Who is Rejuran HB+ for?
People concerned about loss of elasticity, dryness and fine lines, and adults who want to improve tone and overall skin health. Pregnancy or skin disease requires a consultation first.
What should I avoid afterwards?
Avoid washing the face and makeup for 24 hours. For about a week, skip saunas, intense exercise and alcohol, use sunscreen diligently, and do not rub or press the treated area.
What is the procedure — does it hurt?
Numbing cream is applied first. Fine needles deliver the product evenly across the face in roughly 30 minutes. Temporary redness or swelling usually clears within a few days.
When do results appear and how long do they last?
Most people notice improvement within 12 weeks. Results last about six months, and three sessions are recommended for continued improvement.
What is Rejuran HB+?
An injection that combines polynucleotides (PN) and hyaluronic acid (HA) for regeneration and hydration at the same time: PN stimulates skin-cell renewal and elasticity, HA keeps the skin moisturized.

Sources and related searches

People also search: Rejuran Healer vs Rejuran HB+ · Rejuran i for under-eyes

Your doctor

About Dr. Hongseok Kim

Dr. Kim performs your Rejuran himself — from the first skin analysis to the follow-up check.

Dr. Kim focuses on aesthetic dermatology — skin regeneration, facial contour and healthy aging — and builds each plan from a close look at the individual patient's skin and goals, aiming for natural, refined results.

At VOS the same specialist is responsible for the whole course of care: diagnosis, the procedure itself and follow-up. An accurate reading of skin structure and how it changes is what makes results more complete and keeps the risk of side effects low.

Credentials & appointments

Current
Medical Director, VOS Dermatology Clinic
Board-certified dermatologist
Education
Graduated first in class, medical school
Academic appointments
Adjunct Professor, Dept. of Medical Aesthetics, Cheongju University
Adjunct Professor, Dept. of Beauty Medical Science, Dongguk University
Professional leadership
Director, Korean Dermatologist Association (KDA)
Director, Korean Association for Anti-Aging Dermatology (KAAD)
Committees
Academic Committee Member, Korean Dermatological Association
Information Committee Member, Korean Dermatologist Association (KDA)
Memberships
Korean Society for Dermatologic Functional Medicine
Korean Society for Laser Medicine and Surgery

Brand advisory

Skincare
  • The Scent
  • SkinCeuticals
  • La Roche-Posay
  • AHC
  • Bioderma
  • Etat Pur
Injectables
  • Juvelook
  • Revive
  • Lafullen
  • Rejuran
Devices
  • Ulthera
  • Thermage
  • Sofwave
  • CoolSculpting
  • Mirajet
Academic & speaking activities

Lecturing, live demonstrations and brand education — in Korea and across Asia.

presentations & lectures listed
116
years covered by the list
2016–2026
in 2023, the busiest year listed
25
Presentations & lectures per year
  • 2016: 1 listed
  • 2017: 5 listed
  • 2018: 4 listed
  • 2019: 12 listed
  • 2020: 5 listed
  • 2021: 4 listed
  • 2022: 17 listed
  • 2023: 25 listed
  • 2024: 23 listed
  • 2025: 16 listed
  • 2026: 4 listed
  • Dr. Hongseok Kim at JULIA SUMMIT GLOBAL — Juvelook Journey — invited lectureLecture
    JULIA SUMMIT GLOBALJuvelook Journey — invited lecture · 2025
  • Dr. Hongseok Kim at APS Korea 2026 — Aesthetic Plastic Surgery KoreaConference
    APS Korea 2026Aesthetic Plastic Surgery Korea · 2026
  • Dr. Hongseok Kim at 28th KDA Spring Conference — Korean Dermatologist AssociationConference
    28th KDA Spring ConferenceKorean Dermatologist Association · 2026
  • Dr. Hongseok Kim at KOREADERMA 2025 — COEX, SeoulConference
    KOREADERMA 2025COEX, Seoul · 2025
  • Dr. Hongseok Kim at IMLG 2025 — Live injection training for international physiciansLive demo
    IMLG 2025Live injection training for international physicians · 2025
  • Dr. Hongseok Kim at JULIA SUMMIT ASIA 2025 — Presentation, Hong KongLecture
    JULIA SUMMIT ASIA 2025Presentation, Hong Kong · 2025
  • Dr. Hongseok Kim at IMLG 2025 — Faculty & attendeesLive demo
    IMLG 2025Faculty & attendees · 2025
  • Dr. Hongseok Kim at SkinCeuticals — Next Beauty Code, TaiwanBrand event
    SkinCeuticalsNext Beauty Code, Taiwan · 2025
  • Dr. Hongseok Kim at IMLG 2025 — Live demonstration, explained step by stepLive demo
    IMLG 2025Live demonstration, explained step by step · 2025
  • Dr. Hongseok Kim at COSRX — Brand event, SeoulBrand event
    COSRXBrand event, Seoul · 2025

Selected international & major meetings

  1. 2026
    • APS Korea 2026
    • 28th KDA Spring Conference
    • Invited lecture, Baim Global Jupiter Symposium
  2. 2025
    • JULIA SUMMIT GLOBAL – Juvelook Journey
    • JULIA SUMMIT ASIA 2025Hong Kong
    • KOREADERMA 2025
    • SkinCeuticals: Next Beauty CodeTaiwan
    • 9th KDA procedural skills training
  3. 2024
    • AMWC-TDAC Taiwan
    • Juvelook Launching Symposium in Taiwan
    • KSDS 2nd International Congress Seoul
    • 1st Ulthera Focus Group Meeting
Show 2 earlier yearsShow fewer
  1. 2023
    • AMWC Japan
    • 41st Annual Meeting, Japanese Society of Aesthetic Dermatology
    • ACDS 2023
    • MEVOS Dalian
  2. 2022
    • ASLMS (American Society for Laser Medicine & Surgery)
    • 13th I-SWAM Indonesia Convention Exhibition

Broadcast

  • Morning N — hyperhidrosis and choosing cosmetics
  • “Golden time of skin lifespan” (Jul 2021)
  • Park Yong-kwan's Radio Show — regular Monday guest
  • Good Morning — spring sunlight and skin (Mar 2023)
  • Jo Woo-jong's FM Daehaengjin — Dr. Family corner
  • Men On Air — summer skin care

Papers & books

  • Juvelook Comparative Pain Assessment
  • Cosmetic Counseling Expert Course
  • Cosmetic Ingredients for Skin Care

Source: VOS Dermatology's official Korean profile of Dr. Kim.

Meet Dr. Kim
Creator visits

Creators who filmed their treatment at VOS.

Each video comes with Dr. Kim's notes on what was done, why, and the listed price. Opinions are the creators' own; results vary.

Written by Dr. Kim

VOS Dermatology Blog

Plain-language guides written by Dr. Hongseok Kim, board-certified dermatologist — treatments, recovery, cost and planning your visit to Seoul.

Google reviews

What international patients wrote on Google Maps.

Screenshots of public reviews left on Google — in their own words, unedited. Experiences and results vary from person to person.

Google Maps · 27 reviews shownRead all reviews on Google
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Dr. Hongseok Kim on YouTube · @pialnam197K subscribers · skin science explained by the dermatologist you will meet
Watch Dr. Kim

Before you book, hear it from the doctor himself.

Slide through 17 videos on lifting, skin boosters and traveling for treatment. Korean audio — everything plays right here.

Travel"Flying tomorrow, no bruising or swelling?" Top 3 No-Downtime Lifting (Ultherapy prime,Sofwave,Opus)

LiftingAfter Ulthera & Thermage, What's Next? Dermatologist with 21 Years of RF Experience Breaks It Down!

Skin boostersA Dermatologist with 21 Years of Experience Breaks Down the Skin Booster Family Tree

JuvelookMust-Know Before Getting JuveLook! | What It Can & Can’t Do, Clinic Tips by Dr.DTS

JuvelookPairing Juvelook with This Can Double the Firming Effect (And Ease Nodule Concerns)

JuvelookEverything About Juvelook — Effects, Real Treatment Review, Rejuran Comparison

Skin boostersDoctors Won’t Talk About This Treatment Yet… So I’m Revealing Everything | ECM Skin Booster Q&A

Skin boostersWhy does 'that' super famous skin booster contain 'filler' ingredients?

Skin boostersGOURI Is Korea’s Hottest Skin Booster — But What About the Bruising?

Anti-agingSurface Treatments vs Deep Treatments | Which One Actually Makes You Look Younger?

AftercareDid you just pay a fortune for a dermatology treatment? You'll 100% regret skipping this video.

Dr. KimSorry to my patients... I tried it on myself first (21-Year Derm's Self-Treatment Full Process)

BodyTrapezius Slimming for Sharp Shoulders ✨ How to Get That Clean, Angular Look (Spring/Summer Must)

Travel22-Hour Flight + High-Altitude UV: The One Thing a Dermatologist Used the Whole Time

ResearchScientists Erased a “Mark of Aging” Once Thought Irreversible | A New 2026 Aging Study | Dr. PIALNAM

PoresWhy Your Pores Won’t Shrink | What Actually Works? | Dr. DTS

SkincareWhy Your Expensive Vitamin C Isn’t Working|How to Use It for Better Absorption|Dr. PIALNAM

Shorts

VOS Shorts

Get to know VOS in seconds — 60-second answers from Dr. Kim to the questions you’d ask in the chair. Everything plays right here.

How to get Juvelook without side effects

How long does Sofwave last?

Boost Your Results with Sofwave!

RE-TOURN! It's Different from Collagen Injections

Juvelook Skin Rejuvenation Effects

How many Ultherapy Prime shots are enough?

Want to look younger!?

Skin Booster: Myths and Facts

Most of Your Allergy Test Results Came Back Positive?! You Might Have OOO Syndrome!

More Isn’t Always Better!? How to Properly Use Moisturizer

Does Snail Cream Actually Contain Snails?

Hands-Free Exercises to Smooth Out Smile Lines

The Secret Habit of People Who Stay Healthy and Live Longer (Worth Millions)

Cleansing oil for sunscreen? Double cleansing? You’ve been doing it all wrong...

Father's Wisdom on Shaving (Secret to Avoiding Cuts)

If nothing you apply stops the dryness

What if you blindly apply too much sunscreen without knowing 'this ingredient'? Your skin will br...

2 Skincare Ingredients a Dermatologist Will Never Use (Be Extra Careful!)

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